28 September 1926 – 4 June 2019[https://www.nikkei.com/article/DGXMZO45776110W9A600C1CZ8000/ 石坂照子さんが死去 免疫学者] was a [[Japanese|Japanese people]] scientist and [[immunologist]] who along with her husband Kimishige Ishizaka discovered the antibody class [[Immunoglobulin E]] (IgE) in 1966. Their work was regarded as a major breakthrough in the understanding of allergy, and for this work she received the 1972 Passano Award and the 1973 Gairdner Foundation International Award. She was known in the science world for her generosity and collaborative spirit.
She received a doctorate in medicine from Tokyo Women's Medical School in 1949 and a PhD from the University of Tokyo in 1955.
By 1962, the Ishizakas were recruited to the Children's Asthma Research Institute and Hospital (CARIH, later National Jewish Health) in Denver. In 1966, they announced their discovery of the IgE antibody class. At about the same time, S.G.O Johansson and Hans Bennich made the same discovery in Uppsala, Sweden. In April 1969, they published a joint paper .
By 1970, rumors of a merger with the National Jewish Hospital made the couple move to the Allergy and Immunology Center at Johns Hopkins University in Baltimore .
In 1989, she published research demonstrating that a human mast cell also developed from haemopoietic stem cell, something that had been demonstrated before only in mice. The same year, her husband became the first Scientific Director of the La Jolla Institute for Immunology, so she moved to California, and retired in 1993.
For their achievements the couple were awarded the Passano Award in 1972 and the Gairdner Foundation International Award in 1973 and the Borden Award in 1979. Ishizaka was the first female scientist in Japan to receive the Behring Kitasato Prize.
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